Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lhx6  LIM homeobox protein 6
Results	Reference
1	J:203731 Arguello A, Yang X, Vogt D, Stanco A, Rubenstein JL, Cheyette BN, Dapper antagonist of catenin-1 cooperates with Dishevelled-1 during postsynaptic development in mouse forebrain GABAergic interneurons. PLoS One. 2013;8(6):e67679
1*	J:86937 Bithell A, Alberta J, Hornby F, Stiles CD, Williams BP, Expression of the guanine nucleotide exchange factor, mr-gef, is regulated during the differentiation of specific subsets of telencephalic neurons. Brain Res Dev Brain Res. 2003 Dec 19;146(1-2):107-18
1	J:181828 Caronia-Brown G, Grove EA, Timing of cortical interneuron migration is influenced by the cortical hem. Cereb Cortex. 2011 Apr;21(4):748-55
1	J:121077 Colombo E, Collombat P, Colasante G, Bianchi M, Long J, Mansouri A, Rubenstein JL, Broccoli V, Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation. J Neurosci. 2007 Apr 25;27(17):4786-98
1*	J:85473 Corbin JG, Rutlin M, Gaiano N, Fishell G, Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development. 2003 Oct;130(20):4895-906
1	J:317998 Du A, Wu X, Chen H, Bai QR, Han X, Liu B, Zhang X, Ding Z, Shen Q, Zhao C, Foxg1 Directly Represses Dbx1 to Confine the POA and Subsequently Regulate Ventral Telencephalic Patterning. Cereb Cortex. 2019 Dec 17;29(12):4968-4981
1	J:269929 Elbert A, Vogt D, Watson A, Levy M, Jiang Y, Brule E, Rowland ME, Rubenstein J, Berube NG, CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons. J Neurosci. 2019 Jan 2;39(1):177-192
1*	J:93609 Fuccillo M, Rallu M, McMahon AP, Fishell G, Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct;131(20):5031-40
1	J:174118 Fuccillo M, Rutlin M, Fishell G, Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice. Cereb Cortex. 2006 Jul;16 Suppl 1:i96-102
1	J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74
1	J:282137 Gongrich C, Krapacher FA, Munguba H, Fernandez-Suarez D, Andersson A, Hjerling-Leffler J, Ibanez CF, ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons. J Cell Biol. 2020 Jan 6;219(1)
1*	J:48134 Grigoriou M, Tucker AS, Sharpe PT, Pachnis V, Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development. 1998 Jun;125(11):2063-74
1	J:127720 Jepsen K, Solum D, Zhou T, McEvilly RJ, Kim HJ, Glass CK, Hermanson O, Rosenfeld MG, SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature. 2007 Nov 15;450(7168):415-9
1*	J:195139 Kraus P, Sivakamasundari V, Lim SL, Xing X, Lipovich L, Lufkin T, Making sense of Dlx1 antisense RNA. Dev Biol. 2013 Apr 15;376(2):224-35
1	J:321499 Lee DR, Rhodes C, Mitra A, Zhang Y, Maric D, Dale RK, Petros TJ, Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 Feb 17;11:e71864
1	J:119476 Liodis P, Denaxa M, Grigoriou M, Akufo-Addo C, Yanagawa Y, Pachnis V, Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. J Neurosci. 2007 Mar 21;27(12):3078-89
1	J:293452 Liu Z, Zhang Z, Lindtner S, Li Z, Xu Z, Wei S, Liang Q, Wen Y, Tao G, You Y, Chen B, Wang Y, Rubenstein JL, Yang Z, Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development. Cereb Cortex. 2019 Jun 1;29(6):2653-2667
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*	J:173287 Long JE, Swan C, Liang WS, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
1*	J:82310 Marin O, Plump AS, Flames N, Sanchez-Camacho C, Tessier-Lavigne M, Rubenstein JL, Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Development. 2003 May;130(9):1889-901
1	J:197761 McKinsey GL, Lindtner S, Trzcinski B, Visel A, Pennacchio LA, Huylebroeck D, Higashi Y, Rubenstein JL, Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron. 2013 Jan 9;77(1):83-98
1	J:100340 Mori T, Yuxing Z, Takaki H, Takeuchi M, Iseki K, Hagino S, Kitanaka J, Takemura M, Misawa H, Ikawa M, Okabe M, Wanaka A, The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons. Eur J Neurosci. 2004 Jun;19(12):3129-41
1	J:266266 Newman EA, Wu D, Taketo MM, Zhang J, Blackshaw S, Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus. Dev Biol. 2018 Oct 15;442(2):236-248
1	J:198037 Paschou P, Stylianopoulou E, Karagiannidis I, Rizzo R, Tarnok Z, Wolanczyk T, Hebebrand J, Nothen MM, Lehmkuhl G, Farkas L, Nagy P, Szymanska U, Lykidis D, Androutsos C, Tsironi V, Koumoula A, Barta C, Klidonas S, Ypsilantis P, Simopoulos C, Skavdis G, Grigoriou M, Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome. Genes Brain Behav. 2012 Jun;11(4):444-51
1	J:132162 Petryniak MA, Potter GB, Rowitch DH, Rubenstein JL, Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron. 2007 Aug 2;55(3):417-33
1	J:196967 Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Houart C, Meyer G, Blackshaw S, Tole S, LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis. J Neurosci. 2013 Apr 17;33(16):6877-84
1	J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
1*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1*	J:65195 Stoykova A, Treichel D, Hallonet M, Gruss P, Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci. 2000 Nov 1;20(21):8042-50
1	J:226502 Takagi T, Nishizaki Y, Matsui F, Wakamatsu N, Higashi Y, De novo inbred heterozygous Zeb2/Sip1 mutant mice uniquely generated by germ-line conditional knockout exhibit craniofacial, callosal and behavioral defects associated with Mowat-Wilson syndrome. Hum Mol Genet. 2015 Nov 15;24(22):6390-402
1	J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82
1	J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441
1	J:153550 Yu W, Wang Y, McDonnell K, Stephen D, Bai CB, Patterning of ventral telencephalon requires positive function of Gli transcription factors. Dev Biol. 2009 Oct 1;334(1):264-75